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Selected Publications

McDowell CM, Kizhatil K, Elliott MH, et al. Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms. Invest Ophthalmol Vis Sci. 2022 Feb 1;63(2):12. 

Greene AG, Eivers SB, McDonnell F, et al. Differential Lysyl oxidase like 1 expression in pseudoexfoliation glaucoma is orchestrated via DNA methylation. Exp Eye Res. 2020 Dec;201:108349.

McDonnell F, Perkumas KM, Ashpole NE, et al. Shear Stress in Schlemm's Canal as a Sensor of Intraocular Pressure. Sci Rep. 2020 Apr 2;10(1):5804. doi: 10.1038/s41598-020-62730-4. PubMed PMID: 32242066; PubMed Central PMCID: PMC7118084.

McDonnell F, Dismuke WM, Overby DR, Stamer WD. Pharmacological regulation of outflow resistance distal to Schlemm's canal. Am J Physiol Cell Physiol. 2018 Jul 1;315(1):C44-C51.

Keller KE, Bhattacharya SK, Borrás T, Brunner TM, et al. Consensus recommendations for trabecular meshwork cell isolation, characterization and culture. Exp Eye Res. 2018 Jun;171:164-173.

Liu B, Kilpatrick JI, Lukasz B,et al. Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells. Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):803-814.

McDonnell FS, McNally SA, Clark AF, et al. Increased Global DNA Methylation and Decreased TGFβ1 Promoter Methylation in Glaucomatous Lamina Cribrosa Cells. J Glaucoma. 2016 Oct;25(10):e834-e842.

McDonnell F, Irnaten M, Clark AF, et al. Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFβ1 Expression in Human Trabecular Meshwork Cells. PLoS One. 2016;11(4):e0153354.

McDonnell F, O'Brien C, Wallace D. The role of epigenetics in the fibrotic processes associated with glaucoma. J Ophthalmol. 2014;2014:750459.